By Richard R. ed. Gacek
New morphologic proof in human temporal bones from sufferers with vestibular neuronitis, Meniere's disorder, benign paroxysmal positional vertigo, and idiopathic facial paralysis is recommend to help the idea that those neuropathies are because of re-activation of a latent neurotropic virus (Herpes relations) positioned within the sensory ganglia. formerly unreported adjustments point out that the efferent neuronal pathways to the auditory and vestibular finish organs could degenerate due to their direction during the infected vestibular ganglion. Such paralysis of the efferent approach might be chargeable for secondary signs (tinnitus, movement intolerance) linked to those neuropathies. Case histories with magnetic resonance imaging of the 7th and 8th cranial nerves are defined in help of the viral neuropathy inspiration. In end, a few strategies at the boundaries and effectiveness of antiviral remedy are awarded.
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Extra resources for Viral Neuropathies in the Temporal Bone (Advances in Otorhinolaryngology, Vol. 60)
The organ of Corti was normal except for the basal 9 mm where there was a total loss of hair cells. There was a total loss of vestibular neurons (fig. 9, 10). Efferent axons remained in Rosenthal’s canal as well as in the peripheral vestibular nerve branches. The vestibular sense organs were normal. Several degenerated and intact ganglion cells in the MG of the FN were surrounded by a plethora of satellite and inflammatory cells (fig. 11). Although there were many satellite cells in the GG, no degenerated ganglion cells were found (fig.
The large afferents supply the type 1 hair cells with a calyx-like ending, in a 1 : 1 or 1 : 2 ratio (fig. 9). The small afferents supply type 2 hair cells in the vestibular sense organs with small bouton-type endings. Each small afferent fiber branches generously to contact type 2 hair cells over a wide area in the sensory epithelium. There is an orderly distribution of type 1 and type 2 hair cells in the sense organs . In the crista of the three semicircular canals, type 1 hair cells are located primarily at the crest of the crista, whereas type 2 hair cells predominate along the slopes.
Gacek 26 Fig. 17. Drawing of the origin and course of the olivocochlear efferent bundle by Rasmussen . vestibular ganglion before the efferent cochlear fibers emerge as the vestibulocochlear anastomosis (Oort’s), enter Rosenthal’s canal and then travel apically in a spiral direction as the intraganglionic spiral bundle. As the bundle travels apically in the cochlea, it gives off individual fibers which mix with afferent dendrites within the osseous spiral lamina before exiting through the habenula perforata to enter the organ of Corti.