By Antonio V. Delgado-Escueta, Renzo Guerrini MD, Marco T. Medina MD, Pierre Genton MD, Michelle Bureau MD, Charlotte Dravet MD
This quantity is the 1st finished textual content and scientific reference on idiopathic myoclonic epilepsies of infancy, early life, youth, and maturity. The world’s leading specialists describe the phenotypes and subtypes of myoclonic epilepsies and the underlying molecular defects and summarize state-of-the-art advances in molecular genetics that shed new gentle at the etiologies of those syndromes.
The booklet bargains clinicians much-needed assistance in spotting and diagnosing idiopathic myoclonic epilepsies and choosing applicable remedy. each one bankruptcy comprises diagnostic and remedy algorithms to lead practitioners in medical choice making.
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Additional resources for Myoclonic epilepsies
An earlier reflex component at ~42 msec (LLR I) is present in 30% of normal subjects, and at ~70 msec an additional LLR III may occur (30). The reflex jerk was originally called a C- (cortical) reflex, as it was presumed to be cortically mediated (31). Electric or mechanic stimulation of a relevant nerve produces a reflex response that has a latency of 30 to 50 msec for the upper limb and 60 to 70 msec for the lower limb. If the afferent [N20 of somatosensory evoked potentials (SEPs)] and efferent motor-evoked potentials (MEPs) from transcranial magnetic stimulation (TMS) conduction times are subtracted from these latencies, the cortical relay time (CRT) is obtained, corresponding to the intracortical transmission time of myoclonic activity.
Paris, 1899. 4. Genton P, Gélisse P. Seminal citations: juvenile myoclonic epilepsy. Arch Neurol 2001 Sep;58(9):1487–1490. 5. Janz D, Christian W. Impulsiv Petit-Mal. Dtsch Z Nervenheilk 1957;176:346–386. (English translation by P. Genton. In: Malafosse A, Genton P, Hirsch E, Marescaux C, Broglin D, Bernasconi M, eds. Idiopathic generalized epilepsies. London: John Libbey, 1994:229–251). 6. Castells C, Mendilaharsu C. La epilepsia mioclónica bilateral y consciente. Acta Neurol Latinoamer 1958;4:23–48.
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