Encyclopedia of Gerontology, Two-Volume Set, Second Edition by James E. Birren, Suresh I. S. Rattan

By James E. Birren, Suresh I. S. Rattan

Because the first version, the learn literature on getting older maintains to extend swiftly, reflecting either the emerging curiosity of the medical neighborhood and likewise the wishes of a getting old inhabitants. within the 12 months 1900, people over sixty five years of age have been the smallest component to constructed societies. this day they're rising because the greatest.

Aging is a posh means of swap related to affects of a organic, behavioral, social, and environmental nature, all of that are explored within the context of this encyclopedia. the second one version comprises all new articles and entirely new insurance of subject matters that experience visible examine advances.

Also to be had on-line through ScienceDirect (2006) - that includes large shopping, looking out, and inner cross-referencing among articles within the paintings, plus dynamic linking to magazine articles and summary databases, making navigation versatile and straightforward. for additional info, pricing innovations and availability stopover at www.info.sciencedirect.com.

>Organized alphabetically via article title
>Consolidates and summarizes pertinent findings whereas offering extra readings
>Breadth of insurance spans biology, psychology, social technological know-how, wellbeing and fitness technological know-how, and humanities
>Every article features a definition paragraph and a thesaurus of strange terms
>Fully cross-referenced and incorporates a entire topic index
>Online availability through ScienceDirect

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Additional resources for Encyclopedia of Gerontology, Two-Volume Set, Second Edition

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One subject that has not been brought up in the previous discussion is the Gompertz curves. It has been frequently argued that mutations that alter life span in any way must conform to Gompertzian traits. That is, the slope of the mortality curve (which represents the age-specific mortality) must be affected in order for the model to be called a true model of accelerated aging. Not all researchers agree with this criterion, and indeed, the Gompertz equation accepts as valid only those models that display accelerated aging, but it precludes the use of models in which aging occurs prematurely but with the same mortality slope (see Figure 1).

For example, we must be careful to distinguish between the age at which an individual is most likely to occupy the role of general or admiral and the individual’s performance in that role. One early investigation, for instance, looked at the age at which commanders led armies in historic battles without noting whether the battle was won or lost. As a result, the information obtained was very limited in its implications. Another difficulty is even more severe than that seen in the study of political leaders: although military careers can last a long time, the central function of those careers, namely, fighting wars, usually has a much shorter duration.

The exceptions are the PolgAmut and the MsrA À / À mice. Surprisingly, however, the authors also failed to observe age relevance in several wellestablished long-lived models, including Prop 1, IGF1R, GHRHR, and InsR. In contrast, they do find a relevant relationship in the cases of GHR, Pit1, and Shc. Given the close relationship between these many models, it seems likely that this criterion might be too stringent, and/or some of the data were derived without sufficient numbers of animals. This is certainly the case for the MsrA À / À mouse.

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