Comorbidity in Migraine by Jean Schoenen, David W. Dodick, Peter S?ndor

By Jean Schoenen, David W. Dodick, Peter S?ndor

This e-book provides a clinically orientated method of figuring out and treating co-morbid migraine. Case vignettes and administration algorithms will improve the scientific application of the booklet.

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Have you noticeable whatever that wasn't rather there? Heard somebody name your identify in an empty apartment? Sensed a person following you and circled to discover nothing?

Hallucinations don’t belong completely to the insane. even more generally, they're associated with sensory deprivation, intoxication, ailment, or harm. individuals with migraines may even see shimmering arcs of sunshine or tiny, Lilliputian figures of animals and folks. individuals with failing eyesight, sarcastically, might turn into immersed in a hallucinatory visible international. Hallucinations might be caused by an easy fever or maybe the act of waking or falling asleep, while humans have visions starting from luminous blobs of colour to superbly distinct faces or terrifying ogres. those who find themselves bereaved may perhaps obtain comforting “visits” from the departed. In a few stipulations, hallucinations can result in spiritual epiphanies or perhaps the sensation of leaving one’s personal physique.

Humans have continuously sought such life-changing visions, and for millions of years have used hallucinogenic compounds to accomplish them. As a tender general practitioner in California within the Sixties, Oliver Sacks had either a private and a pro curiosity in psychedelics. those, together with his early migraine reports, introduced a lifelong research into the kinds of hallucinatory event.

Here, together with his ordinary beauty, interest, and compassion, Dr. Sacks weaves jointly tales of his sufferers and of his personal mind-altering studies to light up what hallucinations let us know concerning the association and constitution of our brains, how they've got stimulated each culture’s folklore and paintings, and why the potential of hallucination is found in us all, an essential component of the human .

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Extra resources for Comorbidity in Migraine

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57 Kurth T, Schürks M, Logroscino G, Gaziano JM, Buring JE. Migraine. vascular risk, and cardiovascular disease in women. Prospective cohort study. a636. 58 Lee ST, Chu K, Jung KH, et al. Decreased number and function of endothelial progenitor cells in patients with migraine. Neurology 2008;70:1510–17. 59 Kunz GA, Liang G, Cuculi F, et al. Circulating endothelial progenitor cells predict coronary artery disease severity. Am Heart J 2006;152:190–5. 60 Vanmolkot FH, Van Bortel LM, de Hoon JN. Altered arterial function in migraine of recent onset.

Indd 31 1/31/2011 1:04:21 PM 32 Comorbidity in Migraine In observational studies, therefore, the expectation is that migraineurs who are prescribed triptans would be at reduced risk of CVD compared to migraineurs who are not prescribed triptans. Observational studies that compare cardiovascular outcomes in triptan-using versus non-triptan-using migraineurs are thus inherently confounded by indication in a way that would be expected to attenuate or reverse any theoretical increased risk of cardiovascular disease in migraineurs; adjustment for known risk profiles can only partly control for this inherent limitation.

Sándor. © 2011 Blackwell Publishing Ltd. Published 2011 by Blackwell Publishing Ltd. 1 Risk of non-stroke cardiovascular disease from non-clinical populations. Mig or MA Author Source Study subjects Age Risk or odds of CHD in migraineurs vs non-migraineurs [95% CI] CHD outcome Prospective cohort studies MA Gudmundsson et al. 2010 [8] Kurth et al. 5] Mig‡ Kurth et al. 3] MA§ Liew et al. 8] (♀) No CHD deaths (♂) MA** Rose et al. 2004 [13] Blue Mountain Eye Study ARIC – community Coronary revascularization Myocardial infarction Angina Coronary revascularization Myocardial infarction Angina CHD death 12,409 45–64 Fatal/non-fatal CHD Rose angina Mig†† Sternfeld et al.

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