Cavernous Malformations of the Nervous System by Daniele Rigamonti MD

By Daniele Rigamonti MD

Questions concerning the nature and acceptable administration of cavernous malformation (CM) have clouded researchers and people confronted with making scientific judgements for a number of a long time. CMs might be visible as an incidental discovering on MRI stories, or they could current with signs, similar to seizures or intracranial hemorrhage, usually inflicting critical neurologic deficit. Cavernous Malformations of the worried procedure presents a complete and authoritative overview of the present perform in analysis and administration of those cerebrovascular problems. Emphasis has been laid at the knowing of easy sciences with chapters dedicated to knowing of CCM1, 2 and three genes and their function in CCM biology, in addition to scientific genetics. debatable themes which proceed to pose therapy demanding situations similar to protection of anticoagulation and prophylactic administration while pregnant also are mentioned. This booklet may be of curiosity to simple technology researchers, neurosurgeons and vascular neurologists either in educational associations and personal perform.

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12. Cooper, A. , Campeau, N. , et al. Susceptibilityweighted imaging in familial cerebral cavernous malformations. Neurology 2008;71:382. 13. de Souza, J. , Domingues, R. , et al. Susceptibilityweighted imaging for the evaluation of patients with familial cerebral cavernous malformations: a comparison with t2-weighted fast spin-echo and gradient-echo sequences. AJNR Am J Neuroradiol 2008;29:154–158. 14. Lehnhardt, F. , et al. Value of gradient-echo magnetic resonance imaging in the diagnosis of familial cerebral cavernous malformation.

Twin vessels in familial retinal cavernous hemangioma. Am J Ophthalmol 1990;109:285–289. 53. , et al. Spectrum of genotype and clinical manifestations in cerebral cavernous malformations. Neurosurgery 2006;59:1278–1284; discussion 1284–1275. 48. , et al. Vertebral and spinal cavernous angiomas associated with familial cerebral cavernous malformation. Surg Neurol 2009;71:167–171. 54. , et al. Long-term outcome of patients with multiple cerebral cavernous malformations. Neurosurgery 2009;65:450–455; discussion 455.

Cavernous angiomas of the central nervous system. J Neurosurg Sci 1989;33:229–252. 12. Cooper, A. , Campeau, N. , et al. Susceptibilityweighted imaging in familial cerebral cavernous malformations. Neurology 2008;71:382. 13. de Souza, J. , Domingues, R. , et al. Susceptibilityweighted imaging for the evaluation of patients with familial cerebral cavernous malformations: a comparison with t2-weighted fast spin-echo and gradient-echo sequences. AJNR Am J Neuroradiol 2008;29:154–158. 14. Lehnhardt, F.

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